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uniQure jumps after Chardan boosts price target to $175 from $100

Chardan analyst Gbola Amusa raised his price target for uniQure (QURE) to $175 from $100 to reflect the company's opportunity in Huntington's disease. The stock in morning trading is up 4.5%, or $2.63, to $61.64. uniQure, a Chardan Top Pick for 2019, could be headed towards a $5B-$10B valuation as support emerges for what could be a "best-in-class, breakthrough" Huntington's disease franchise, Amusa tells investors in a research note. In the second half of 2019, uniQure is expected to make AMT-130 the first one-time gene theraphy to enter the clinic... -The Fly

NY Fed: Manufacturing "Business activity picked up significantly in New York State"

From the NY Fed: Empire State Manufacturing Survey Business activity picked up significantly in New York State, according to firms responding to the May 2019 Empire State Manufacturing Survey. The headline general business conditions index climbed eight points to 17.8, its highest level in six months. New orders and shipments also grew at a faster pace than in recent months. Delivery times held steady, and inventories moved slightly lower. Labor market indicators pointed to small increases in employment and hours worked. The index for number of... -Calculated Risk

Fly Intel: Top five analyst downgrades

Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Solid Biosciences (SLDB) downgraded to Underperform from Neutral at Credit Suisse, to Sell from Neutral at Goldman Sachs, and to Neutral from Buy at Chardan. 2. Shopify (SHOP) downgraded to Underweight from Equal Weight at Morgan Stanley with analyst Brian Essex citing his view that the stock is not deserving of the same multiple as high-growth U.S. 3. Deere (DE) downgraded to Underweight from Neutral at JPMorgan with analyst Ann Duignan saying she sees "rapidly... -The Fly

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